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This is one of nature's way of controlling the structure of proteins

Consistent with these findings, a study of 1335 Norwegian nurses reported that NSW was associated with a higher prevalence of self-reported common cold, pneumonia/bronchitis, sinusitis, and gastrointestinal infections, highlighting the role of disrupted sleep and circadian misalignment in increasing susceptibility to infections 123

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A few points on Vitamin B12 deficiency: Vitamin B12 (cobalamin) is important for cellular metabolism (DNA synthesis), mitochondrial metabolism as well as neuronal health